Reduced Blood-brain Barrier Penetration of Sarecycline Relative to Minocycline in Rats Corresponds with Lipophilicity and Low Vestibular Side Effects

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Linda Stein-Gold
Angela Moore
S. Ken Tanaka
Jodi Johnson
Ayman Grada


Pharmacology, Sarecycline, Blood-Brain Barrier, Vestibular Side Effects


Abstract not available.


1. Pariser DM, Green LJ, Lain EL, et al. Safety and Tolerability of Sarecycline for the Treatment of Acne Vulgaris: Results from a Phase III, Multicenter, Open-Label Study and a Phase I Phototoxicity Study. Journal of Clinical and Aesthetic Dermatology. 2019;12(11):E53-E62.

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