Herpes Zoster in a 2-Year-Old Child After a Single Dose of Varicella Vaccine

Main Article Content

Hope Barone
Mary Veremis
Stuart Gildenberg


Herpes Zoster, Childhood herpes zoster, Vaccine strain herpes zoster, Oka herpes zoster vaccine


In this report, we describe a rare case of an immunocompetent 2-year-old child who developed herpes zoster (HZ) in the same dermatomal distribution as the vaccination site received several months prior. Although most cases of HZ caused by the vaccine-strain virus follow a mild disease course, affected patients are contagious to household members and may nevertheless develop severe complications such as herpes ophthalmicus and meningoencephalitis. Consideration of this entity and associated complications is critical for dermatologists when evaluating similar appearing eruptions.


1. Centers for Disease Control and Prevention (CDC. Prevention of varicella. MMWR. 2007;56:1-40.

2. Peterson N, Goodman S, Peterson M, Peterson W. Herpes zoster in children. Cutis. 2016;98(2):94-5.

3. Dagrosa AT, Collins LK, Chapman MS. Atypical herpes zoster presentation in a healthy vaccinated pediatric patient. Cutis. 2017;100(5):303-4.

4. Guffey DJ, Koch SB, Bomar L, Huang WW. Herpes zoster following varicella vaccination in children. Cutis. 2017;99(3):207-11.

5. Dreyer S, Hemarajata P, Hogeling M, Henderson GP. Pediatric vaccine‐strain herpes zoster: a case series. Pediatric Dermatology. 2017;34(6):665-7.

6. Weinmann S, Chun C, Schmid DS, Roberts M, Vandermeer M, Riedlinger L, Bialek SR, Marin M. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005-2009. J Infect Dis. 2013;208:1859-1868.

7. Marzano AV, Genovese G, Fabbrocini G, Pigatto P, Monfrecola G, Piraccini BM, Veraldi S, Rubegni P, Cusini M, Caputo V, Rongioletti F. Varicella-like exanthem as a specific COVID-19–associated skin manifestation: Multicenter case series of 22 patients. J Am Acad Dermatol. 2020.

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)