Idiopathic Aseptic Facial Granuloma

Main Article Content

Caroline Garraway
Thy Huynh
Robert Brodell
Vinayak K. Nahar

Keywords

Rosacea; Acne; Children

Abstract

Pyodermite froide du visage, otherwise known as idiopathic facial aseptic granuloma (IFAG), is a benign lesion exclusively seen in children and presents as a cold abscess on the face.1 We report a case of a  14-year-old male with IFAG who failed initial treatment with oral doxycycline, but responded  to treatment with oral 13-cis-retinoic acid, oral trimethoprim-sulfamethoxazole and intralesional triamcinolone injections over a 7 month period. 

References

1. Roul S, Léauté-Labrèze C, Boralevi F et al. Idiopathic aseptic facial granuloma (pyodermite froide du visage): a pediatric entity? Arch Dermatol 2001;137:1253-1255.

2. Miconi F, Principi N, Cassiani L, et al. A Cheek Nodule in a Child: Be Aware of Idiopathic Facial Aseptic Granuloma and Its Differential Diagnosis. Int J Environ Res Public Health. 2019;16(14):2471. Published 2019 Jul 11. doi:10.3390/ijerph16142471

3. Orion C, Sfecci A, Tisseau L, Darrieux L, Safa G. Idiopathic facial aseptic granuloma in a 13-year-old boy dramatically improved with oral doxycycline and topical metronidazole: Evidence for a link with childhood rosacea. Case Rep. Dermatol. 2016;8:197-201. doi:10.1159/000447624.

4. Boralevi F, Léauté C, Lepreus S et al. Idiopathic facial aseptic granuloma: a multicenter prospective study of 30 cases. Br J Dermatol 2007;156:705-708

5. Lee, G. and Fischer, G. (2020), Isotretinoin therapy for idiopathic aseptic facial granuloma. Australas J Dermatol. doi:10.1111/ajd.13257

6. Neri I, Raone B, Dondi A et al. Should idiopathic facial aseptic granuloma be considered granulomatous rosacea? Report of three pediatric cases. Pediatr. Dermatol. 2013;30:109-11.

7.Satta, R., Montesu, M.A., Biondi, G. and Lissia, A. (2016), Idiopathic facial aseptic granuloma: case report and literature review. Int J Dermatol, 55: 1381-1387. doi:10.1111/ijd.13161

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