SARS-Cov-2 Infection Uncovering Latent Mycobacterium Leprae Infection

Main Article Content

Christopher Mancuso, DO, MHS
Paloma Reiter, DO
Regina Zambrano, DO
Ritu Saini, MD
Suzanne Sirota-Rozenberg, DO

Keywords

Mycobacterium leprae, Mycobacterium, Leprosy, COVID, COVID-19, SARS-Cov-2, Leonine facies, Hansen's disease

Abstract

Leprosy is a chronic granulomatous infection caused by the bacteria Mycobacterium leprae. It can remain dormant in a patient without any symptoms until triggered by a stressor on the body. During the coronavirus disease 2019 (COVID-19) pandemic, a significant amount of emotional and psychological stress was endured by patients. In addition, many patients experienced exacerbations of their preexisting conditions. Few reports have described cases of leprosy with concurrent COVID-19. This brief article presents a case of newly diagnosed leprosy in a middle-aged male following a COVID-19 infection. To our knowledge, this is the first reported case of its kind in the United States.

References

1. Rathod S, Suneetha S, Narang T, et al. Management of Leprosy in the Context of COVID-19 Pandemic: Recommendations by SIG Leprosy (IADVL Academy). Indian Dermatol Online J. 2020;11(3):345-348. Published 2020 May 10. doi:10.4103/idoj.IDOJ_234_20

2. SchmSchmitz V, Dos Santos JB. COVID-19, leprosy, and neutrophils. PLoS Negl Trop Dis. 2021;15(1):e0009019. Published 2021 Jan 7. doi:10.1371/journal.pntd.0009019itz

3. Antunes DE, Goulart IMB, Goulart LR. Will cases of leprosy reaction increase with COVID-19 infection? PLoS Negl Trop Dis. 2020;14:e0008460 10.1371/journal.pntd.0008460

4. Santos VS, Quintans-Júnior LJ, Barboza WS, Araújo AAS, Martins-Filho PR. Clinical characteristics and outcomes in patients with COVID-19 and leprosy [published online ahead of print, 2020 A

5. Nery JA, Bernardes Filho F, Quintanilha J, Machado AM, Oliveira Sde S, Sales AM. Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy. An Bras Dermatol. 2013;88(5):787-792. doi:10.1590/abd1806-4841.20132004

6. Bilik L, Demir B, Cicek, D. Leprosy Reactions. Hansen's Disease - The Forgotten and Neglected Disease. 2019. doi: 10.5772/intechopen.72481

7. Thng ZX, De Smet MD, Lee CS, et al. COVID-19 and immunosuppression: a review of current clinical experiences and implications for ophthalmology patients taking immunosuppressive drugs [published online ahead of print, 2020 Jun 12]. Br J Ophthalmol. 2020;bjophthalmol-2020-316586. doi:10.1136/bjophthalmol-2020-316586

8. Liu D, Ahmet A, Ward L, et al. A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol. 2013;9(1):30. Published 2013 Aug 15. doi:10.1186/1710-1492-9-30

9. Barnes BJ, Adrover JM, Baxter-Stoltzfus A, et al. Targeting potential drivers of COVID-19: Neutrophil extracellular traps. J Exp Med. 2020;217(6):e20200652. doi:10.1084/jem.20200652

10. Mehta P, McAuley DF, Brown M, et al. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395(10229):1033-1034. doi:10.1016/S0140-6736(20)30628-0

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