Successful Dupilumab Treatment of Atopic Dermatitis in a Liver Transplant Patient

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Amanda Krenitsky
Sairekha Ravichandran
Joel Cohen
Jonathan Braue
Lilia Correa-Selm


Transplant, Dupixent, Dupilumab, Atopic Dermatitis, scaly, AD


Atopic dermatitis (AD) in liver transplant (LT) recipients is well-documented, despite frequent use of immunosuppressants in these patients. In a liver transplant population, the prevalence of AD in children and adults is 27.6% and 10.3%, respectively.1 However, there is dearth ofliterature regardingtreatment of this population, and standard regimens are not well-defined.2-4 Here, we report a case of successful treatment of AD in an orthotopic LT patient with dupilumab. 


1. Topal E, Çatal F, Selimoğlu MA, et al. Acquired atopic disease after liver transplantation in children; similarities to and differences from adults: a preliminary study. Eur J Gastroenterol Hepatol. Sep 2014;26(9):1055-9. doi:10.1097/meg.0000000000000142

2. Ludriksone L, Elsner P, Malessa C, Settmacher U, Schliemann S. Effectiveness and safety of dupilumab for atopic dermatitis in a liver transplant recipient: a case report. J Dtsch Dermatol Ges. Jul 2020;18(7):740-742. doi:10.1111/ddg.14074

3. Kha C, Raji K, Chisolm S. Treatment of Atopic Dermatitis With Dupilumab in a Renal Transplant Patient. Dermatitis. Mar/Apr 2020;31(2):e17-e18. doi:10.1097/der.0000000000000560

4. Jamgochian M, Milgraum D, Milgraum S, Pappert A. Dupilumab as treatment for atopic dermatitis in a pediatric heart transplant patient: A case report. Dermatol Ther. Nov 2020;33(6):e14018. doi:10.1111/dth.14018

5. Tsianakas A, Ständer S. Dupilumab: a milestone in the treatment of atopic dermatitis. Lancet. Jan 2 2016;387(10013):4-5. doi:10.1016/s0140-6736(15)00389-x

6. Product Approval Information - Licensing Action Dupixent (dupilumab). Available online at: (accessed on 06 Sep 2021).

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