Main Article Content
Cutaneous Rosai-Dorfman disease, Rosai Dorfman disease, histiocytosis
Cutaneous Rosai-Dorfman Disease (CRDD) is an uncommon benign histiocytosis of unknown etiology. CRDD is oftentimes misdiagnosed because it has variable clinical manifestations, particularly in the absence of lymphadenopathy. We report a case of a 23-year-old African American woman presenting with clustered nodular plaques on her right thigh, buttocks, back, and chest for the past two years. History, clinical, histopathological, and immunochemistry findings corresponded with CRDD, and as such, she was treated with halobetasol propionate 0.05% cream twice daily.
Wang K-H, Chen W-Y, Liu H-N, Huang C-C, Lee W-R, Hu C-H. Cutaneous Rosai–Dorfman disease: clinicopathological profiles, spectrum and evolution of 21 lesions in six patients. Br J Dermatol. 2006;154:277-86.
Rubenstein MA, Farnsworth NN, Pielop JA, Orengo IF, Curry JL, Drucker CR, et al. Cutaneous Rosai-Dorfman disease. Dermatol Online J. 2006;12(1):8.
Farooq U, Chacon AH, VIncek V, Elgart GW. Purely cutaneous Rosai-Dorfman disease with immunohistochemistry. Indian J Dermatol. 2013;58(6):447-52.
Hinojosa T, Ramos E, Lewis DJ, Angel Ld, Vangipuram R, Peranteau AJ, et al. Cutaneous Rosai-Dorfman disease: A separate clinical entity. J Dermatol & Dermatol Surg. 2017;21:107-9.
Jia J, Tian Q, Zhang H, Zheng Y. An unusual case of multiple cutaneous Rosai-Dorfman disease involving two separate parts of the body. Int J Dermatol. 2017;56:576-8.
Kinio AE, Sawchuk MA, Pratt M. Atypical primary cutaneous Rosai-Dorfman disease: A case report. J Cutan Med Surg. 2017;21(5):460-3.
Khoo JJ, Othman Rb. Cutaneous Rosai-Dorfman disease. Malaysian J Pathol. 2007;29(1):49-52.
Middel P, Hemmerlein B, Fayyazi A, Kaboth U, Radzun HJ. Sinus histiocytosis with massive lymphadenopathy: Evidence for its relationship to macrophages and for a cytokine-related disorder. Histopathology. 1999;35:525-33.
Landim FM, Rios HdO, Costa CO, Feitosa RGF, Costa AAA. Cutaneous Rosai-Dorfman disease. An Bras Dermatol. 2009;84(3):1-5.
Salim A, Williamson M, Barker F, Hughes J. Steroid responsive cutaneous Rosai–Dorfman disease associated with uveitis and hypothyroidism. Clin Exp Dermatol. 2002;27:277-9.
Kong Y, Kong J, Shi D, Lu H, Zhu X, Wang J. Cutaneous Rosai-Dorfman disease a clinical and histopathologic study of 25 cases in China. Am J Surg Pathol. 2007;31:341-50.
Lu C-I, Kuo T-t, Wong W-R, Hong H-S. Clinical and histopathologic spectrum of cutaneous Rosai-Dorfman disease in Taiwan. J Am Acad Dermatol. 2004;51:931-9.
Scheel MM, Rady PL, Tyring SK, Pandya AG. Sinus histiocytosis with massive lymphadenopathy: Presentation as giant granuloma annulare and detection of human herpesvirus 6. J Am Acad Dermatol. 1997;37:643-6.
Annesi G, Giannetti A. Purely cutaneous Rosai-Dorfman disease. Br J Dermatol. 1996;134:749-53.
Lai FM-M, Lam WY, Chin CW, Ng WL. Cutaneous Rosai-Dorfman disease presenting as a suspicious breast mass. J Cutan Pathol. 1994;21:377-82.