Main Article Content
neoplasms (benign), neoplasms (malignant), dermatopathology
Nevus sebaceous is a congenital epidermal hamartoma characterized by hyperplastic changes to the epidermis and adnexa. Nevus sebaceous is associated with an elevated risk of cutaneous neoplasms, most often benign; however, malignant neoplasms, most notably basal cell carcinoma, can also present in these patients. Although a rare occurrence, more often affecting adult patients, squamous cell carcinomas have also been reported to arise at the site of pre-existing nevus sebaceous. Herein we report a unique case of a patient with basal cell carcinoma and squamous cell carcinoma arising concurrently in the same nevus sebaceous.
2. Idriss MH, Elston DM. Secondary neoplasms associated with nevus sebaceus of Jadassohn: a study of 707 cases. Journal of the American Academy of Dermatology 2014;70(2):332-37
3. Cribier B, Scrivener Y, Grosshans E. Tumors arising in nevus sebaceus: a study of 596 cases. Journal of the American Academy of Dermatology 2000;42(2):263-68
4. Jaqueti, G., Requena, L. and Yus, E. (2000). Trichoblastoma Is the Most Common Neoplasm Developed in Nevus Sebaceus of Jadassohn. The American Journal of Dermatopathology, 22(2), pp.108-118.
5. Eisen DB, Michael DJ. Sebaceous lesions and their associated syndromes: part I. Journal of the American Academy of Dermatology 2009;61(4):549-60
6. Rosen H, Schmidt B, Lam HP, Meara JG, Labow BI. Management of Nevus Sebaceous and the Risk of Basal Cell Carcinoma: An 18‐Year Review. Pediatric dermatology 2009;26(6):676-81
7. Wilson-Jones E. Naevus sebaceus. A report of 140 cases with special regard to the development of secondary malignant tumours. Br J Dermatol 1970;82:99-117
8. Ball, E., Hussain, M. and Moss, A. (2005). Squamous cell carcinoma and basal cell carcinoma arising in a naevus sebaceous of Jadassohn: case report and literature review. Clinical and Experimental Dermatology, 30(3), pp.259-260.
9. Arshad, A., Azman, W. and Kreetharan, A. (2008). Solitary sebaceous nevus of Jadassohn complicated by squamous cell carcinoma and basal cell carcinoma. Head & Neck, 30(4), pp.544-548.
10. Turan E, Buyukgural B, Ilhan Celik O. Simultaneous occurrence of two squamous cell carcinomas developing in a nevus sebaceous. Archives of Iranian medicine 2015;18(4):253-6 doi: 015184/aim.0012.
11. Belhadjali H, Moussa A, Yahia S, Njim L, Zakhama A, Zili J. Simultaneous Occurrence of two Squamous Cell Carcinomas within a Nevus Sebaceous of Jadassohn in an 11‐Year‐Old Girl. Pediatric dermatology 2009;26(2):236-37