Spontaneous Resolution of Asymptomatic Papules on the Face of a Two-Year-Old

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Taylor Shea Novice
Alex Glazer


benign cephalic histiocytosis, papules, pediatric, histiocytosis, langerhans cell histiocytosis


A nine-month old male infant presented with multiple, asymptomatic, and yellow-to-pink lesions on his face. Physical exam revealed multiple 2-5 mm reddish brown papules on the forehead, nose, cheeks, and chin Laboratory findings, developmental milestones, and ophthalmology exam were within normal limits, and biopsy was consistent with benign cephalic histiocytosis. Lesions spontaneously involuted at age 18 months without treatment, and by age two, the lesions had fully resolved without sequelae.


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