Successful Treatment of Pityriasis Rubra Pilaris with Brodalumab

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Umair Khan
Nahla Shihab
Robert G Phelps
Mark Lebwohl


pityriasis rubra pilaris, brodalumab, methotrexate


Pityriasis Rubra Pilaris (PRP) is a rare inflammatory skin disease with highly variable clinical appearance. Treatment of PRP remains a challenge and has been mostly guided by case reports and case series. We report the first case of pityrisis rubra pilaris that is successfully treated with combination therapy of brodalumab and methotrexate.


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