About the Journal

SKIN is a bi-monthly, peer-reviewed, online medical journal dedicated to providing an enhanced route to disseminate new dermatologic knowledge on all aspects of cutaneous disease.
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Current Issue

Vol. 5 No. 1 (2021): January Issue & Poster Presentations (WC21 Dermatology Conference®)

Published: 2021-01-08

Editorials

Should the Black Box Warning of Brodalumab and Apremilast Deter Prescribing in Psoriasis Patients with Depression?

Graham H Litchman DO, MS, Quinn Thibodeaux, Ryan Rivera-Oyola, John Koo, Rick Fried, Gary Goldenberg, George Han, Sylvia Hsu, Leon Kircik, Melissa Knuckles, Andrea Murina, Jashin Wu, Mark Lebwohl

Page 1-6

Original Research

What is the True Etiology of “Recurrent Shingles”?

Ramya Vangipuram, Harrison Nguyen, Stephen Tyring

Page 7-12

Genomic Atypia to Enrich Melanoma Positivity in Biopsied Lesions: Gene Expression and Pathology Findings From a Large U.S. Registry Study

Brook Brouha, Laura Ferris, Maral Skelsey, Gary Peck, Jim Rock, Anh Nguyen, Zuxu Yao, Michael Howell, Burkhard Jansen, Clay Cockerell

Page 13-18

Research Letters

Perceptions of Teledermatology among people with Hidradenitis Suppurativa

Ashley Eichelberger, Melissa Butt, Colleen Silva, Aretha Mosley, Joslyn Kirby

Page 19-21

Preventative Medicine in Dermatologic Care: Providing Immunization Education and Convenient Pneumococcal Immunizations for Patients Receiving Immunosuppressive Therapy

Ashleigh Workman, Josh Lindsley, Nathaniel Web, Thaddeus Miller, Erica Stockbridge, Jean Charles, Stephen Weis

Page 25-28

The Ongoing Impact of COVID-19 on US Dermatology Practices

Graham Litchman, Justin Marson, Darrell Rigel

Page 29-33

COVID Concepts

Brief Articles

TP53 Mutated Metastatic Basal Cell Carcinoma Responsive to Sonidegib

Brian Wanner, Austin Cusick, Jyoti Kapil, Stephen D'Addario

Page 37-40

A Case of ALK-Negative Anaplastic Large Cell Lymphoma Presenting as a Solitary Cutaneous Nodule

Venkat Sumanth Potluri, Ronnie Youssef, Raymond Fertig, Parneet Dhaliwal

Page 60-64

Short Communications

Toluidine blue for extramammary Paget’s disease in Mohs micrographic surgery

Roxana Mititelu, Claudia Flores-Echaiz, Manish Kanna

Page 68-70

Distinguishing Features: Linear Rashing is Not Always Koebnerization

Nneamaka Ezekwe, Thy Huynh, Robert Brodell

Page 71-74

Imatinib-Induced Acquired Dermal Melanocytosis

Anna Eversman, Sakeena Fatima, Kord Honda, Mara G Beveridge

Page 75-77

Expanding Armor-Like Scales in a Middle-Aged Woman

Christina E. Bax, Robert J. Smith, Cory L. Simpson

Page 78-79

Pruritic Rash and Oral Erosions During Nivolumab Treatment for Melanoma

Shant Tamazian, Emily Y. Chu, Cory L. Simpson

Page 80-82

Poster Presentations from WC21 Clinical Dermatology Conference®: Skin Cancer

Performance of a 35-Gene Expression Profile Test in Suspicious Pigmented Lesions of the Head and Neck

Clay Cockerell, Matthew Goldberg, Sarah Estrada, Gregory Hosler, Howard Martin, Brooke Russell, Olga Zolochevska, Natalie Depcik-Smith, Nathan Cleaver

Page s1

Restricted Mean Survival Time and Cure-Rate Modeling in Estimating Relapse-Free Survival Benefit With Adjuvant Dabrafenib + Trametinib Treatment in Melanoma

John Kirkwood, Reinhard Dummer, Axel Hauschild, Mario Santinami, Victoria Atkinson, Vanna Sileni, James Larkin, Marta Nyakas, Andrew Haydon, Caroline Dutriaux, Jacob Schachter, Caroline Robert, Laurent Mortier, Hiya Banerjee, Tomas Haas, Monique Tan, Mike Lau, Dirk Schadendorf, Georgina Long, Mario Mandala

Page s2

Interim Analysis of Phase 2 Results for Cemiplimab in Patients with Metastatic Basal Cell Carcinoma (mBCC) who Progressed on or are Intolerant to Hedgehog Inhibitors (HHIs)

Karl Lewis, Katty Peris, Aleksandar Sekulic, Alexander Stratigos, Lara Dunn, Zeynep Eroglu, Anne Lynn Chang, Michael Migden, Siyu Li, Suk-Young Yoo, Kosalai Mohan, Ebony Coates, Emmanuel Okoye, Jean-Francois Baurain, Oliver Bechter, Axel Hauschild, Marcus Butler, Leonel Hernandez-Aya, Lisa Licitra, Rogerio Neves, Emily Ruiz, Frank Seebach, Israel Lowy, Timothy Bowler, Matthew Fury

Page s3

Primary Analysis of Phase 2 Results for Cemiplimab in Patients (pts) with Locally Advanced Basal Cell Carcinoma (laBCC) who Progress on or are Intolerant to Hedgehog Inhibitors (HHIs)

Alexander Stratigos, Aleksandar Sekulic, Ketty Peris, Oliver Bechter, Martin Kaatz, Karl Lewis, Nicole Basset-Segiun, Anne Lynn Chang, Stephanie Dalle, Almudena Fernandez Orland, Lisa Licitra, Caroline Robert, Claas Ulrich, Axel Hauschild, Michael Migden, Reinhard Dummer, Siyu Li, Kosalai Mohan, Ebony Coates, Vladimir Jankovic, Nathalie Flaschi, Emmanuel Okoye, Ioannis Bassukas, Carmen Loquai, Vincent De Giorgi, Zeynep Eroglu, Ralf Gutzmer, Jens Ulrich, Susana Puig, Frank Seebach, Gavin Thurston, Israel Lowy, Timothy Bowler, Matthew Fury

Page s4

Cemiplimab Improves Health-Related Quality of Life (HRQoL) and Reduces Pain in Patients with Advanced Cutaneous Squamous Cell Carcinoma (CSCC): Results from a Post Hoc Exploratory Analysis of a Phase 2 Clinical Trial

Michael Migden, Danny Rischin, Medha Sasane, Vera Mastey, Anna Pavlick, Chrysalyne Schmults, Zhen Chen, Alexander Guminski, Axel Hauschild, Denise Bury, Stacie Hudgens, Anne Lynn Chang, Guilherme Rabinowits, Sherrif Ibrahim, Matthew Fury, Israel Lowy, Siyu Li, Chieh-I Chen

Page s5

Skin Health & Hygiene

Atopic Dermatitis

Efficacy and Safety of Ruxolitinib Cream for the Treatment of Atopic Dermatitis: Pooled Analysis of Two Phase 3, Randomized, Double-Blind Studies

Kim Papp, Jacek Szepietowski, Leon Kircik, Darryl Toth, Michael Kuligowski, May Venturanza, Kang Sun, Eric Simpson

Page s8

Specifically Targeting Interleukin-13 with Tralokinumab Improved Sleep in Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Trials in Patients with Atopic Dermatitis

Jonathan Silverberg, Sebastien Barbarot, Melinda Gooderham, Jan Simon, Eric Simpson, Azra Kurbasic, Christina Olsen, Michael Cork

Page s9

Conjunctivitis in Tralokinumab-Treated Adult Patients with Moderate-To-Severe Atopic Dermatitis: Pooled Results from Five Clinical Trials

Andreas Wollenberg, Lisa Beck, Marjolein de Bruin Weller, Rebecca Zachariae, Christina Olsen, Jacob Thyssen

Page s10

Efficacy and Safety of Crisaborole in Patients With Mild-to-Moderate Atopic Dermatitis With and Without Food Allergies

Michael Blaiss, Michael Cork, Peter Lio, Aharon Kessel, Liza Takiya, John Werth, Michael O'Connell, Chuanbo Zang, Jonathan Spergel

Page s12

Efficacy and Safety of Crisaborole in Patients With Mild-to-Moderate Atopic Dermatitis With and Without Comorbid Allergic Rhinitis

Jonathan Spergel, Michael Blaiss, Peter Lio, Aharon Kessel, Liza Takiya, John Werth, Michael O'Connell, Chuanbo Zang, Michael Cork

Page s13

Dermatopharmacology

Sarecycline Demonstrates Narrow spectrum Antibacterial Activity and Anti inflammatory Effect in Animal Models

Christopher Bunick, James Del Rosso, Stephen Tyring, Michael Draper, Jodi Johnson, Ayman Grada

Page s14

Psoriasis

Bimekizumab Safety in Patients with Moderate to Severe Psoriasis: Analysis of Pooled Data from Phase 2 and 3 Clinical Trials

K Reich, A Blauvelt, M Lebwohl, KA Papp, P Rich, B Strober, D De Cuyper, C Madden, L Peterson, V Vanvoorden, RB Warren

Page s21

Acne & Rosacea

Efficacy and Safety of Tazarotene 0.045% Lotion in Female Patients with Moderate-to-Severe Acne: Post Hoc Analysis by Age

Linda Stein Gold, Hilary Baldwin, Fran Cook-Bolden, Lawrence Green, Glynis Ablon, Neil Sadick, Jonathan Weiss, Eric Guenin

Page s23

Pruritus & Prurigo Nodularis

Modulation of the Mu and Kappa Opioid Axis for the Treatment of Chronic Pruritus

Sarina Elmariah, Sarah Chisolm, Thomas Sciascia, Shawn Kwatra

Page s30

The Role of Kappa- and Mu-Opioid Receptors in Pruritus

Brian Kim, Thomas Sciascia, Gil Yosipovitch

Page s31

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